4L™ + POLYNUCLEOTIDES
THE POWER OF 4L™ TECHNOLOGY
Driven by a commitment to innovation in regenerative aesthetics, PRODERMIS has developed 4L™ Technology — a next-generation formulation system that sets a new benchmark in product quality and performance. Each of the four Ls represents a pillar of the technology: Purity of raw materials, Performance through advanced molecular stabilization, Precision in particle structure and injection behavior, and Protection of skin health through biocompatibility.
This technology ensures the integrity of active ingredients such as Polynucleotides and Hyaluronic Acid, enabling them to work synergistically at an optimal concentration and bioavailability. The result is a safe, stable, and effective product that delivers superior outcomes across a range of aesthetic indications — with less downtime and more consistent results.
4L™ Technology is the scientific foundation behind every PRODERMIS product — empowering practitioners and elevating patient outcomes.
Polynucleotides: enhancing filler performance
What sets PRODERMIS apart is its integration of Polynucleotides (PN) into the cross-linked HA filler matrix — a pioneering combination that delivers noticeably superior performance compared to traditional fillers. This unique formulation results in a filler that is not only volumizing, but also structurally intelligent, adapting to facial dynamics with greater elasticity and cohesiveness.
The inclusion of PN improves injection behavior, making the filler smoother to place, easier to mold, and more predictable in outcome. It also enhances the stability and longevity of the result, reducing migration and breakdown over time. Practitioners report increased control and patient satisfaction — with results that feel as good as they look.
With Polynucleotides, PRODERMIS isn't just filling — it's performing at a higher standard.
The Benefits of Prodermis
Controlled Handling
- Exceptionally smooth extrusion with reduced injection force
- Stable glide performance ensures greater control during placement
- Textured syringe grip improves handling even with gloves
Formulation Integrity
- Powered by 4L™ Technology for unmatched product stability and purity
- High cohesiveness and elasticity reduce filler migration
- Uniform particle distribution ensures consistent injection flow
Precision Placement
- Designed for optimal mouldability and tissue integration
- Advanced viscoelastic properties adapt to facial movement
- Trusted performance across multiple anatomical planes
Visual Dosing Control
- Clear, easy-to-read graduations for accurate volume tracking
- Transparent barrel for full visibility of product flow
- Efficient dosing supports multi-area treatments in one session
Enhanced Patient Outcomes Formulated for Precision & Performance
PRODERMIS Prosculpt fillers are engineered to deliver exceptional lift, integration, and longevity across a full spectrum of aesthetic indications. Each product in the range combines cross-linked Hyaluronic Acid with Polynucleotides (PN) using our proprietary 4L™ Technology, which ensures purity, stability, and seamless tissue adaptation.
This advanced formulation enhances rheological performance, offering practitioners superior control, smoother extrusion, and consistent results — even in complex treatment areas. Patients benefit from natural-looking volume, improved skin quality, and long-lasting definition, with reduced risk of swelling, migration, or irregularities.
Science-Backed Innovation
At PRODERMIS, innovation is driven by science. Our R&D team works closely with medical professionals to continually optimise formulation performance and clinical outcomes. From particle engineering to biostimulatory integration, every detail of the Prosculpt range is informed by clinical feedback and laboratory excellence.
As global demand for non-surgical aesthetics continues to grow, PRODERMIS stands at the forefront of regenerative injectable science — offering next-generation solutions that redefine what’s possible with dermal fillers.
Lift with precision. Sculpt with confidence. Treat with science.
